Cephalexin for dogs is one of the most commonly prescribed antibiotics for dogs with skin infections, especially those caused by bacteria like Staphylococcus pseudintermedius. It’s effective in treating conditions like pyoderma, hot spots, and abscesses. However, the best antibiotic for a dog with a skin infection depends on the specific type of bacteria involved, which may require a culture and sensitivity test. While cephalexin works well for many dogs, other antibiotics like amoxicillin-clavulanate or clindamycin may be used based on the infection’s severity and resistance profile. Always consult a veterinarian for the proper antibiotic and dosage.